Pre_GI Gene

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Host: NC_012658 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012658:3778822 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
3778822377925943850S ribosomal protein L13QuickGO ontologyBLASTP
37793803780120741tRNA pseudouridine synthase AQuickGO ontologyBLASTP
37801203780923804cobalt transport permeaseQuickGO ontologyBLASTP
37809203781786867cobalt transporter ATP-binding subunitQuickGO ontologyBLASTP
37817713782619849cobalt transporter ATP-binding subunitQuickGO ontologyBLASTP
3782710378305134250S ribosomal protein L17QuickGO ontologyBLASTP
37830953784042948DNA-directed RNA polymerase subunit alphaQuickGO ontologyBLASTP
3784110378473062130S ribosomal protein S4QuickGO ontologyBLASTP
3784765378516339930S ribosomal protein S11QuickGO ontologyBLASTP
3785181378555237230S ribosomal protein S13QuickGO ontologyBLASTP
3785665378577811450S ribosomal protein L36QuickGO ontologyBLASTP
37857953786013219translation initiation factor IF-1QuickGO ontologyBLASTP
37860213786302282hypothetical proteinBLASTP
37863173787066750methionine aminopeptidaseQuickGO ontologyBLASTP
37870663787716651adenylate kinaseQuickGO ontologyBLASTP
378774037890171278preprotein translocase subunit SecYQuickGO ontologyBLASTP
3789018378945844150S ribosomal protein L15QuickGO ontologyBLASTP
3789478378965718050S ribosomal protein L30QuickGO ontologyBLASTP
3789671379016849830S ribosomal protein S5QuickGO ontologyBLASTP
3790186379054536050S ribosomal protein L18QuickGO ontologyBLASTP
3790564379110654350S ribosomal protein L6QuickGO ontologyBLASTP
3791130379152839930S ribosomal protein S8QuickGO ontologyBLASTP
3791558379174318630S ribosomal protein S14QuickGO ontologyBLASTP
3791760379230254350S ribosomal protein L5QuickGO ontologyBLASTP
3792325379264231850S ribosomal protein L24QuickGO ontologyBLASTP
3792666379303436950S ribosomal protein L14QuickGO ontologyBLASTP
3793069379332325530S ribosomal protein S17QuickGO ontologyBLASTP
3793345379355721350S ribosomal protein L29QuickGO ontologyBLASTP
3793547379399044450S ribosomal protein L16QuickGO ontologyBLASTP
3794008379467967230S ribosomal protein S3QuickGO ontologyBLASTP
3794697379503233650S ribosomal protein L22QuickGO ontologyBLASTP
3795054379533828530S ribosomal protein S19QuickGO ontologyBLASTP
3795408379624183450S ribosomal protein L2QuickGO ontologyBLASTP
3796296379658929450S ribosomal protein L23QuickGO ontologyBLASTP
3796589379720962150S ribosomal protein L4QuickGO ontologyBLASTP
3797234379786363050S ribosomal protein L3QuickGO ontologyBLASTP
3797953379826130930S ribosomal protein S10QuickGO ontologyBLASTP
379866337998561194elongation factor TuQuickGO ontologyBLASTP
379989538019642070elongation factor GQuickGO ontologyBLASTP
3802037380250747130S ribosomal protein S7QuickGO ontologyBLASTP
3802670380304737830S ribosomal protein S12QuickGO ontologyBLASTP
38031233803365243ribosomal protein L7Ae family proteinQuickGO ontologyBLASTP
380348738070233537DNA-directed RNA polymerase subunit betaQuickGO ontologyBLASTP
380704438107693726DNA-directed RNA polymerase subunit betaQuickGO ontologyBLASTP