Pre_GI Gene

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Host: NC_012580 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012580:796387 Vibrio cholerae M66-2 chromosome II, complete sequence

Host Lineage: Vibrio cholerae; Vibrio; Vibrionaceae; Vibrionales; Proteobacteria; Bacteria

General Information: Vibrio cholerae M66-2 was isolated from the 1937 cholera outbreak in the Makassar area of Indonesia. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Vibrio cholerae can colonize the mucosal surface of the small intestines of humans where it will cause cholera, a severe and sudden onset diarrheal disease. One famous outbreak was traced to a contaminated well in London in 1854 by John Snow, and epidemics, which can occur with extreme rapidity, are often associated with conditions of poor sanitation. The disease has a high lethality if left untreated, and millions have died over the centuries. There have been seven major pandemics between 1817 and today. Six were attributed to the classical biotype, while the 7th, which started in 1961, is associated with the El Tor biotype.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
7963877978081422GntR family transcriptional regulatorQuickGO ontologyBLASTP
7979377995291593cytochrome d ubiquinol oxidase subunit IQuickGO ontologyBLASTP
7995428006781137cytochrome d ubiquinol oxidase subunit IIQuickGO ontologyBLASTP
801500801703204hypothetical proteinBLASTP
8019208032451326D-serine dehydrataseQuickGO ontologyBLASTP
803453804397945DNA-binding transcriptional regulator DsdCQuickGO ontologyBLASTP
8046978057731077hydrolaseQuickGO ontologyBLASTP
805881806042162integrase-like proteinQuickGO ontologyBLASTP
806571806726156hypothetical proteinBLASTP
806671807051381hypothetical proteinBLASTP
807076807471396hypothetical proteinBLASTP
8074838085471065hypothetical proteinBLASTP
8085608096691110hypothetical proteinBLASTP
8097208107811062hypothetical proteinBLASTP
810916811089174hypothetical proteinBLASTP
8118788129091032L-threonine 3-dehydrogenaseQuickGO ontologyBLASTP
81291281410511942-amino-3-ketobutyrate coenzyme A ligaseQuickGO ontologyBLASTP
815262816023762transcriptional regulator LuxR familyQuickGO ontologyBLASTP
816123817061939LysR family transcriptional regulatorQuickGO ontologyBLASTP
817055817438384glyoxylase I family proteinQuickGO ontologyBLASTP
8175168189281413hypothetical proteinBLASTP