Pre_GI Gene

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Host: NC_012473 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012473:46000 Bacillus cereus 03BB102 plasmid p03BB102_179, complete sequence

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
46748478841137hypothetical proteinBLASTP
4859449547954hypothetical proteinBLASTP
49567510661500hypothetical proteinBLASTP
5108351532450hypothetical proteinBLASTP
5155751952396hypothetical proteinBLASTP
52175534881314surface layer proteinQuickGO ontologyBLASTP
53607559672361hypothetical proteinBLASTP
5609356254162hypothetical proteinBLASTP
5643156622192hypothetical proteinBLASTP
5699857858861Flp pilus assembly protein CpaBQuickGO ontologyBLASTP
5787558696822SAF domain familyQuickGO ontologyBLASTP
58713601461434bacterial type IIIV secretion system proteinQuickGO ontologyBLASTP
6013961071933hypothetical proteinBLASTP
6121761939723hypothetical proteinBLASTP
6198262188207hypothetical proteinBLASTP
6225262455204hypothetical proteinBLASTP
6252862728201hypothetical proteinBLASTP
6280763415609hypothetical proteinBLASTP
63490645691080hypothetical proteinBLASTP
64600665251926hypothetical proteinBLASTP
6656067108549hypothetical proteinBLASTP
6718667728543hypothetical proteinBLASTP
6812868946819hypothetical proteinBLASTP
6929869849552hypothetical proteinBLASTP
69962717371776hypothetical proteinBLASTP
71727730401314hypothetical proteinBLASTP
7309973260162hypothetical proteinBLASTP
7337074275906hypothetical proteinBLASTP
7454274730189hypothetical proteinBLASTP
7497575310336hypothetical proteinBLASTP
7537775727351hypothetical proteinBLASTP
7572876642915hypothetical proteinBLASTP
76645787352091hypothetical proteinBLASTP
78766828034038hypothetical proteinBLASTP
82800850042205peptidase M23M37 family proteinQuickGO ontologyBLASTP