Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:5239944 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
52399445240822879hypothetical proteinBLASTP
52410045241507504conserved hypothetical protein TIGR00246QuickGO ontologyBLASTP
52415435241728186hypothetical proteinBLASTP
524178252429571176serine proteaseQuickGO ontologyBLASTP
52430215243815795metallo-beta-lactamase family proteinQuickGO ontologyBLASTP
52437995244641843yycI proteinQuickGO ontologyBLASTP
524462252459381317YycH proteinQuickGO ontologyBLASTP
524593552477761842sensory box histidine kinase YycGQuickGO ontologyBLASTP
52477805248487708DNA-binding response regulator YycFQuickGO ontologyBLASTP
5249004524908178tRNA-AspQuickGO ontologyBLASTP
5249098524917477tRNA-GluQuickGO ontologyBLASTP
524940352506921290adenylosuccinate synthetaseQuickGO ontologyBLASTP
525090852522691362replicative DNA helicaseQuickGO ontologyBLASTP
5252297525274344750S ribosomal protein L9QuickGO ontologyBLASTP
525274052547131974DHH subfamily 1 proteinQuickGO ontologyBLASTP
52547925255730939hypothetical proteinBLASTP
5255808525604123430S ribosomal protein S18QuickGO ontologyBLASTP
52560875256617531single-stranded DNA-binding proteinQuickGO ontologyBLASTP
5256635525692529130S ribosomal protein S6QuickGO ontologyBLASTP
525711752582171101GTP-binding protein YchFQuickGO ontologyBLASTP