Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:5126186 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
51254555126189735putative ABC transporter permease proteinQuickGO ontologyBLASTP
51261865127088903ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
51272855128040756methionine aminopeptidase type IQuickGO ontologyBLASTP
512886851388039936lpxtg-motif cell wall anchor domain proteinQuickGO ontologyBLASTP
513929051406901401putative aminopeptidaseQuickGO ontologyBLASTP
51408395141213375hypothetical proteinBLASTP
51412395141910672hypothetical proteinBLASTP
51418945142208315hypothetical proteinBLASTP
51421955142722528RNA polymerase sigma-70 factor ECF subfamilyQuickGO ontologyBLASTP
514287451445441671arginyl-tRNA synthetaseQuickGO ontologyBLASTP
51445445144981438hypothetical proteinBLASTP
51451845146170987hypothetical proteinBLASTP