Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:5094009 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
509400950950491041sua5yciOyrdCywlC family proteinQuickGO ontologyBLASTP
50951585095616459hypothetical proteinBLASTP
50956665096541876putative stage II sporulation protein RQuickGO ontologyBLASTP
50966455097496852protein-glutamine-N5 methyltransferase release factor-specificQuickGO ontologyBLASTP
509749650985721077peptide chain release factor 1QuickGO ontologyBLASTP
50987125099299588thymidine kinaseQuickGO ontologyBLASTP
5099408509965324650S ribosomal protein L31QuickGO ontologyBLASTP
510005751013281272transcription termination factor RhoQuickGO ontologyBLASTP
51017675102732966fructose-16-bisphosphatase class IIQuickGO ontologyBLASTP
510285051041391290UDP-N-acetylglucosamine 1-carboxyvinyltransferase 2QuickGO ontologyBLASTP
51041565104380225hypothetical protein
51044705105327858fructose-bisphosphate aldolase class IIQuickGO ontologyBLASTP
51055385105906369sporulation initiation phosphotransferase FQuickGO ontologyBLASTP
51061085106632525hypothetical proteinBLASTP
510666451082711608CTP synthaseQuickGO ontologyBLASTP
51085295109059531DNA-directed RNA polymerase delta subunitQuickGO ontologyBLASTP
51092155109844630transcriptional regulator TetR familyQuickGO ontologyBLASTP
510990951110481140acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
511107051122151146acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
511227351131248523-hydroxyacyl-CoA dehydrogenaseQuickGO ontologyBLASTP