Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:5055184 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
50551845056026843ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
505620850572151008ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
505734350583621020stage II sporulation protein DQuickGO ontologyBLASTP
505872350600271305UDP-N-acetylglucosamine 1-carboxyvinyltransferase 1QuickGO ontologyBLASTP
50600675060771705hypothetical proteinBLASTP
50608235061059237hypothetical proteinBLASTP
506127350627931521NADH dehydrogenase ubiquinone N subunitQuickGO ontologyBLASTP
506279550642971503NADH dehydrogenase ubiquinone M subunitQuickGO ontologyBLASTP
506429450661561863NADH dehydrogenase ubiquinone L subunitQuickGO ontologyBLASTP
50661865066500315NADH dehydrogenase ubiquinone K subunitQuickGO ontologyBLASTP
50664935067017525NADH dehydrogenase ubiquinone J subunitQuickGO ontologyBLASTP
50670145067433420NADH dehydrogenase ubiquinone I subunitQuickGO ontologyBLASTP
506745950684601002NADH dehydrogenase ubiquinone H subunitQuickGO ontologyBLASTP
506846050695601101NADH dehydrogenase ubiquinone D subunitQuickGO ontologyBLASTP
506956550706201056NADH dehydrogenase subunit cQuickGO ontologyBLASTP
50706175071135519NADH dehydrogenase ubiquinone B subunitQuickGO ontologyBLASTP
50711265071494369NADH dehydrogenase ubiquinone A subunitQuickGO ontologyBLASTP
507178550745142730sensory boxGGDEF family proteinQuickGO ontologyBLASTP
50745885075241654hypothetical proteinBLASTP
50752895076080792hypothetical proteinBLASTP
50762025076603402ATP synthase F1 epsilon subunitQuickGO ontologyBLASTP
507662450780331410ATP synthase F1 beta subunitQuickGO ontologyBLASTP