Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:4908245 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
490824549097561512TPR domain proteinQuickGO ontologyBLASTP
49098964910408513bacterial transferase hexapeptide domain proteinQuickGO ontologyBLASTP
49104324911082651hydrolase haloacid dehalogenase-like familyQuickGO ontologyBLASTP
49111504911962813prolipoprotein diacylglyceryl transferaseQuickGO ontologyBLASTP
49119874912916930HPrSer kinasephosphataseQuickGO ontologyBLASTP
49130734913453381hypothetical proteinBLASTP
49135694914018450hypothetical proteinBLASTP
491407849169542877excinuclease ABC A subunitQuickGO ontologyBLASTP
491696049189361977excinuclease ABC B subunitQuickGO ontologyBLASTP
49190884919261174putative lipoproteinQuickGO ontologyBLASTP
49195654920185621hypothetical proteinBLASTP
49201824920943762transcriptional regulator MerR familyQuickGO ontologyBLASTP
49210434921270228hypothetical proteinBLASTP
49212874921679393hypothetical proteinBLASTP
49216764921897222hypothetical proteinBLASTP
49219104922107198DNA-binding proteinQuickGO ontologyBLASTP
492244249234641023hypothetical proteinBLASTP
49236204924513894transcriptional regulator LysR familyQuickGO ontologyBLASTP
49245654924933369transcriptional regulator MerR familyQuickGO ontologyBLASTP
49249384925483546FMN reductase NADPH-dependentQuickGO ontologyBLASTP
49254864925845360ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
49259514926262312hypothetical proteinBLASTP
492633049280451716ABC transporter permeaseATP-binding proteinQuickGO ontologyBLASTP
492835949295431185hypothetical proteinBLASTP
492965349310891437carboxyl-terminal proteaseQuickGO ontologyBLASTP
49312084932101894cell division ABC transporter permease protein FtsXQuickGO ontologyBLASTP
49320914932777687cell division ABC transporter ATP-binding protein FtsEQuickGO ontologyBLASTP
49330644933387324cytochrome c-551QuickGO ontologyBLASTP
49336424933800159hypothetical proteinBLASTP
493506749375742508preprotein translocase SecA subunitQuickGO ontologyBLASTP
49378514938393543ribosomal subunit interface proteinQuickGO ontologyBLASTP
49384184938552135hypothetical proteinBLASTP
49387174938920204cold shock protein CspCQuickGO ontologyBLASTP
49390414939745705comF operon protein 3QuickGO ontologyBLASTP
493974549410941350comF operon protein 1QuickGO ontologyBLASTP
494122249425321311putative cell wall endopeptidase NlpCP60 familyQuickGO ontologyBLASTP
49427864943100315hypothetical proteinBLASTP
49432744944116843degV family proteinQuickGO ontologyBLASTP
49443564944991636conserved hypothetical protein TIGR00257QuickGO ontologyBLASTP
494506649462021137transcription antiterminator LytR familyQuickGO ontologyBLASTP
494623749473521116UDP-N-acetylglucosamine 2-epimeraseQuickGO ontologyBLASTP