Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:4867210 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
486721048696482439ribonuclease RQuickGO ontologyBLASTP
48697914870534744carboxylesteraseQuickGO ontologyBLASTP
48706934870926234preprotein translocase SecG subunitQuickGO ontologyBLASTP
48710214871713693hypothetical proteinBLASTP
48717104872078369LrgA family proteinQuickGO ontologyBLASTP
48723544873304951inosine-uridine preferring nucleoside hydrolase family proteinQuickGO ontologyBLASTP
487335548746501296enolaseQuickGO ontologyBLASTP
487468148762101530phosphoglycerate mutase 23-bisphosphoglycerate-independentQuickGO ontologyBLASTP
48762074876962756triosephosphate isomeraseQuickGO ontologyBLASTP
487699548781791185phosphoglycerate kinaseQuickGO ontologyBLASTP
487831948793231005glyceraldehyde-3-phosphate dehydrogenase type IQuickGO ontologyBLASTP
487935048803781029gapA transcriptional regulator CggRQuickGO ontologyBLASTP
48805154880760246glutaredoxin family proteinQuickGO ontologyBLASTP
488077048820771308RNA polymerase sigma-54 factorQuickGO ontologyBLASTP
48829724883145174hypothetical protein
48831784883426249hypothetical protein
48835074884283777hypothetical protein
48845464884668123hypothetical protein
488582048869261107hypothetical proteinBLASTP
48869754887253279hypothetical protein
48873474887934588hypothetical proteinBLASTP
48889094889064156hypothetical protein
48895104890118609resolvaserecombinaseQuickGO ontologyBLASTP
489075448919741221hypothetical proteinBLASTP
48920064892191186hypothetical protein
48924634892681219hypothetical protein
48926814893292612hypothetical protein
48933234894180858hypothetical proteinBLASTP
48943444894532189hypothetical protein
48945294895224696hypothetical proteinBLASTP
48958984896866969site-specific recombinase phage integrase familyQuickGO ontologyBLASTP
48973474897553207hypothetical proteinBLASTP
48976474898132486putative lipoproteinQuickGO ontologyBLASTP