Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:4691251 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
46912514691718468hypothetical proteinBLASTP
46918374692550714hypothetical proteinBLASTP
469289846942741377glycyl-tRNA synthetaseQuickGO ontologyBLASTP
46943124694695384putative comA operon proteinQuickGO ontologyBLASTP
46947914695534744hypothetical proteinBLASTP
46955854696178594bioY family proteinQuickGO ontologyBLASTP
46962244697111888UTP-glucose-1-phosphate uridylyltransferaseQuickGO ontologyBLASTP
469722046989441725phosphoglucomutasephosphomannomutase family proteinQuickGO ontologyBLASTP
46990884699693606hypothetical proteinBLASTP
469977647012601485leucyl aminopeptidaseQuickGO ontologyBLASTP
47014064702065660hypothetical proteinBLASTP
47021194702436318hypothetical proteinBLASTP
47024334702939507mutTnudix family proteinQuickGO ontologyBLASTP
470306347042741212pyridine nucleotide-disulphide oxidoreductaseQuickGO ontologyBLASTP
47047344705723990pyridine nucleotide-disulphide oxidoreductaseQuickGO ontologyBLASTP
4705790471607610287cell surface proteinQuickGO ontologyBLASTP