Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:4515909 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
45159094516340432hypothetical proteinBLASTP
45167144516992279hypothetical proteinBLASTP
45170274517209183hypothetical proteinBLASTP
45172114517447237hypothetical proteinBLASTP
45177034518197495transcriptional regulator CarD familyQuickGO ontologyBLASTP
45182704519055786glucose 1-dehydrogenaseQuickGO ontologyBLASTP
45190694519926858glucose uptake proteinQuickGO ontologyBLASTP
45199634520382420hypothetical proteinBLASTP
45204764520709234molybdopterin converting factor subunit 1QuickGO ontologyBLASTP
45207124521176465molybdopterin converting factor subunit 2QuickGO ontologyBLASTP
45211734521688516molybdopterin-guanine dinucleotide biosynthesis protein BQuickGO ontologyBLASTP
452165845229471290molybdopterin biosynthesis protein MoeAQuickGO ontologyBLASTP
45230314523516486molybdenum cofactor biosynthesis protein CQuickGO ontologyBLASTP
452355545245681014putative molybdopterin biosynthesis protein MoeBQuickGO ontologyBLASTP
452458545255981014molybdenum cofactor biosynthesis protein AQuickGO ontologyBLASTP
452575345284042652collagen triple helix repeat domain proteinQuickGO ontologyBLASTP
45285784528907330hypothetical proteinBLASTP
45289224529146225hypothetical proteinBLASTP
45292244529529306rhodanese-like domain proteinQuickGO ontologyBLASTP
45297304529912183hypothetical proteinBLASTP
452996245310861125putative homoserine O-acetyltransferaseQuickGO ontologyBLASTP
45312724531502231hypothetical protein
45314624531848387hypothetical proteinBLASTP
453203745334041368spore germination protein GerHAQuickGO ontologyBLASTP
453342145345151095spore germination protein GerHBQuickGO ontologyBLASTP
453449145355701080spore germination protein GerHCQuickGO ontologyBLASTP
45356614535846186hypothetical proteinBLASTP
45360354536457423hypothetical proteinBLASTP
45365024537377876VrrB proteinQuickGO ontologyBLASTP
45374544537606153hypothetical proteinBLASTP
453763445400422409leucyl-tRNA synthetaseQuickGO ontologyBLASTP
454051745417101194putative permeaseQuickGO ontologyBLASTP