Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:4400420 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
44004204400881462hypothetical proteinBLASTP
440144444025621119sporulation integral membrane protein YtvIQuickGO ontologyBLASTP
44031594403548390putative fxsA cytoplasmic membrane proteinQuickGO ontologyBLASTP
440374744055041758pyruvate kinaseQuickGO ontologyBLASTP
440555844065179606-phosphofructokinaseQuickGO ontologyBLASTP
44066464407620975acetyl-CoA carboxylase carboxyl transferase alpha subunitQuickGO ontologyBLASTP
44076084408477870acetyl-CoA carboxylase carboxyl transferase beta subunitQuickGO ontologyBLASTP
44086634409307645transcriptional regulator GntR familyQuickGO ontologyBLASTP
440932244105601239putative malate dehydrogenaseQuickGO ontologyBLASTP
441066444139873324DNA polymerase III alpha subunitQuickGO ontologyBLASTP
44141054414443339hypothetical proteinBLASTP
44144404414943504hypothetical proteinBLASTP
44149954415927933DHH subfamily 1 proteinQuickGO ontologyBLASTP
44162844416472189hypothetical proteinBLASTP
44164804416743264group-specific proteinQuickGO ontologyBLASTP
44168334416952120hypothetical proteinBLASTP
44170614417324264group-specific proteinQuickGO ontologyBLASTP
441749144188041314thioesterase family proteinQuickGO ontologyBLASTP
44190494419210162hypothetical proteinBLASTP