Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:3705500 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
37055113705738228KH domain proteinQuickGO ontologyBLASTP
3705753370602527330S ribosomal protein S16QuickGO ontologyBLASTP
370612637074751350signal recognition particle proteinQuickGO ontologyBLASTP
37074883707820333hypothetical proteinBLASTP
37079553708944990signal recognition particle-docking protein FtsYQuickGO ontologyBLASTP
370896037125293570chromosome segregation SMC proteinQuickGO ontologyBLASTP
37126763713413738ribonuclease IIIQuickGO ontologyBLASTP
37134723713705234acyl carrier proteinQuickGO ontologyBLASTP
371377537145157413-oxoacyl-acyl-carrier-protein reductaseQuickGO ontologyBLASTP
37145153715459945malonyl CoA-acyl carrier protein transacylaseQuickGO ontologyBLASTP
37154743716466993fatty acidphospholipid synthesis protein PlsXQuickGO ontologyBLASTP
37164633717056594hypothetical proteinBLASTP
371714537191932049ATP-dependent DNA helicase RecGQuickGO ontologyBLASTP
371948337211591677putative phosphataseQuickGO ontologyBLASTP
37211823721544363hypothetical proteinBLASTP
3721923372211118950S ribosomal protein L28QuickGO ontologyBLASTP