Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:3661912 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
366191236631531242zinc protease insulinase familyQuickGO ontologyBLASTP
36632403664139900putative polysaccharide deacetylaseQuickGO ontologyBLASTP
366429136664292139polyribonucleotide nucleotidyltransferaseQuickGO ontologyBLASTP
3666590366685927030S ribosomal protein S15QuickGO ontologyBLASTP
36669603667931972riboflavin biosynthesis protein RibFQuickGO ontologyBLASTP
36679753668898924tRNA pseudouridine synthase BQuickGO ontologyBLASTP
36689853669341357ribosome-binding factor AQuickGO ontologyBLASTP
36693573669638282hypothetical proteinBLASTP
366963536716952061translation initiation factor IF-2QuickGO ontologyBLASTP
36717003672011312ribosomal protein L7A familyQuickGO ontologyBLASTP
36720123672284273hypothetical proteinBLASTP
367229636734021107N utilization substance protein AQuickGO ontologyBLASTP
36734203673890471hypothetical proteinBLASTP
367422336756741452DNA polymerase III PolC-typeQuickGO ontologyBLASTP
3675629367571486Group II catalytic intronQuickGO ontology
367573636775501815reverse transcriptaseendonuclease proteinQuickGO ontologyBLASTP
367827836811902913DNA polymerase III PolC-typeQuickGO ontologyBLASTP