Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:3625800 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
36258003626231432hypothetical proteinBLASTP
362623536277641530tRNA-i6A37 thiotransferase enzyme MiaBQuickGO ontologyBLASTP
36281923629058867putative pyruvate ferredoxin oxidoreductase beta subunitQuickGO ontologyBLASTP
362904536308021758putative pyruvate ferredoxin oxidoreductase alpha subunitQuickGO ontologyBLASTP
36310303631953924renal dipeptidase family proteinQuickGO ontologyBLASTP
36320133632273261stage V sporulation protein SQuickGO ontologyBLASTP
36324223633216795phosphoesterase family proteinQuickGO ontologyBLASTP
363338236349441563HDIGHDKH domain proteinQuickGO ontologyBLASTP
363542636364571032protein RecAQuickGO ontologyBLASTP
363660236378401239competencedamage-inducible protein CinAQuickGO ontologyBLASTP
36378613638439579CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferaseQuickGO ontologyBLASTP
36385033639414912hypothetical proteinBLASTP
36394363640221786ACT domain proteinQuickGO ontologyBLASTP
36403613640609249hypothetical proteinBLASTP
36406853641398714oxidoreductase short-chain dehydrogenasereductase familyQuickGO ontologyBLASTP
364150236427881287zinc protease insulinase familyQuickGO ontologyBLASTP
364278936440631275hypothetical proteinBLASTP
36442623645221960sugar ABC transporter permease proteinQuickGO ontologyBLASTP
364522236462801059sugar ABC transporter permease proteinQuickGO ontologyBLASTP
364627336478051533sugar ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
364791436489811068lipoprotein Bmp familyQuickGO ontologyBLASTP