Pre_GI Gene

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Host: NC_012472 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012472:3503000 Bacillus cereus 03BB102, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
35031153504062948hypothetical proteinBLASTP
35040763504648573thiJpfpI family proteinQuickGO ontologyBLASTP
35046453505223579hypothetical proteinBLASTP
35054783505774297hypothetical proteinBLASTP
35058783506318441hypothetical proteinBLASTP
350634835074031056conserved repeat domain proteinQuickGO ontologyBLASTP
350745335085231071hypothetical proteinBLASTP
350880135163637563conserved repeat domain proteinQuickGO ontologyBLASTP
35164263516932507ccdC proteinQuickGO ontologyBLASTP
35170233517730708cytochrome c-type biogenesis protein CcdAQuickGO ontologyBLASTP
35182173519125909transporter DrugMetabolite Exporter familyQuickGO ontologyBLASTP
351921335203581146thermostable carboxypeptidase 1QuickGO ontologyBLASTP
35203963521340945bacitracin transport permeaseQuickGO ontologyBLASTP
35213333522244912bacitracin transport ATP-binding proteinQuickGO ontologyBLASTP
35223353522910576hypothetical proteinBLASTP
35231413524046906putative als operon regulatory protein AlsRQuickGO ontologyBLASTP
35241993524564366hypothetical proteinBLASTP
35245613525238678hypothetical proteinBLASTP
35252513525664414mutTnudix family proteinQuickGO ontologyBLASTP