Pre_GI Gene

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Host: NC_012207 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012207:2573562 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
25735622574089528putative lipoproteinQuickGO ontologyBLASTP
25741642574550387hypothetical proteinBLASTP
25746072574945339hypothetical proteinBLASTP
257497525766211647putative NAD dependent malate oxidoreductaseQuickGO ontologyBLASTP
257661825781891572putative integral membrane transport proteinQuickGO ontologyBLASTP
25786642579596933putative cysteine synthase AQuickGO ontologyBLASTP
25796002580289690putative serine acetyltransferaseQuickGO ontologyBLASTP
25807052581673969hypothetical proteinBLASTP
258173725828551119hypothetical proteinBLASTP
25829752583931957hypothetical proteinBLASTP
258456225870422481putative transmembrane transport proteinQuickGO ontologyBLASTP
25870552587450396putative transmembrane transport proteinQuickGO ontologyBLASTP
258753625887771242PE-PGRS family proteinQuickGO ontologyBLASTP
2589276258934873tRNA-AsnQuickGO ontology
25894662589885420putative lipoprotein lppQQuickGO ontologyBLASTP
25901412590398258hypothetical proteinBLASTP
259040225923211920putative DNA primaseQuickGO ontologyBLASTP
259232625936211296deoxyguanosinetriphosphate triphosphohydrolase-like proteinQuickGO ontologyBLASTP
259369025956721983putative transmembrane proteinQuickGO ontologyBLASTP
25957572595939183putative EsaT-6 like protein 6QuickGO ontologyBLASTP
259592325973291407PPE family proteinQuickGO ontologyBLASTP