Pre_GI Gene

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Host: NC_012207 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012207:1097228 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
109722810986011374PE-PGRS family proteinQuickGO ontologyBLASTP
10989661099658693mycobacterial persistence regulatorQuickGO ontologyBLASTP
109965811011721515putative two component sensor kinaseQuickGO ontologyBLASTP
110121611026101395putative serine proteaseQuickGO ontologyBLASTP
11026101103155546putative pterin-4-alpha-carbinolamine dehydrataseQuickGO ontologyBLASTP
11031751103630456large-conductance mechanosensitive channelQuickGO ontologyBLASTP
11039531104699747putative adhesion component transport ATP-binding protein ABC transporterQuickGO ontologyBLASTP
110469211072592568putative adhesion component transport transmembrane protein ABC transporterQuickGO ontologyBLASTP
110726611084261161hypothetical proteinBLASTP
11085551109532978putative polyprenyl-diphosphate synthaseQuickGO ontologyBLASTP
11095931110249657hypothetical proteinBLASTP
11103221110654333hypothetical serine rich proteinQuickGO ontologyBLASTP
11107281111321594hypothetical proteinBLASTP
11114221112342921putative UTP--glucose-1-phosphate uridylyltransferaseQuickGO ontologyBLASTP
111241911136991281putative molybdopterin biosynthesis proteinQuickGO ontologyBLASTP
11137621114373612putative ribosomal-protein-alanine acetyltransferaseQuickGO ontologyBLASTP
111453411156101077putative transmembrane proteinQuickGO ontologyBLASTP
11157841116014231hypothetical proteinBLASTP
11160111116262252hypothetical proteinBLASTP
11164431116874432hypothetical proteinBLASTP
111689811178991002hypothetical proteinBLASTP