Pre_GI Gene

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Host: NC_012125 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012125:4559990 Salmonella enterica subsp. enterica serovar Paratyphi C strain

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The genome of this strain harbors a large pathogenicity island, SPI7, with genes coding for the Vi (virulence) antigen and other genes potentially associated with virulence. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
455999045619601971Vi polysaccharide export proteinQuickGO ontologyBLASTP
456198045632841305Vi polysaccharide export inner-membrane proteinQuickGO ontologyBLASTP
45633074563948642Vi polysaccharide export ATP-binding proteinQuickGO ontologyBLASTP
45640284564822795Vi polysaccharide export inner-membrane proteinQuickGO ontologyBLASTP
456483245658991068Vi polysaccharide export proteinQuickGO ontologyBLASTP
456594445676801737Vi polysaccharide biosynthesis protein TviEQuickGO ontologyBLASTP
456768045701752496Vi polysaccharide biosynthesis proteinQuickGO ontologyBLASTP
457019945712451047Vi polysaccharide biosynthesis protein epimeraseQuickGO ontologyBLASTP
457124845725251278Vi polysaccharide biosynthesis protein UDP-glucoseGDP-mannose dehydrogenaseQuickGO ontologyBLASTP
45727704573201432Vi polysaccharide biosynthesis proteinQuickGO ontologyBLASTP
45738494574037189hypothetical proteinBLASTP
457416245756731512DNA helicaseQuickGO ontologyBLASTP
457568145772461566hypothetical proteinBLASTP