Pre_GI Gene

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Host: NC_011896 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011896:3252925 Mycobacterium leprae Br4923, complete genome

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
115661566putative chromosomal replication initiator proteinQuickGO ontologyBLASTP
208132801200putative DNA polymerase III beta subunitQuickGO ontologyBLASTP
328144381158putative DNA replication and SOS induction proteinQuickGO ontologyBLASTP
44355004570hypothetical proteinBLASTP
522972652037putative DNA gyrase subunit BQuickGO ontologyBLASTP
7318110673750putative DNA gyrase subunit AQuickGO ontologyBLASTP
1119512106912hypothetical proteinBLASTP
124041247976tRNA-AlaQuickGO ontologyBLASTP
1285613230375hypothetical proteinBLASTP
1377513966192hypothetical proteinBLASTP
325053532529282394putative secreted proteinQuickGO ontologyBLASTP
325292532565453621hypothetical proteinBLASTP
325811832594941377bifunctional thioredoxin reductasethioredoxinQuickGO ontologyBLASTP
325962732608471221putative hydrolaseQuickGO ontologyBLASTP
32608443261623780hypothetical proteinBLASTP
326197632629831008putative cell division proteinQuickGO ontologyBLASTP
326298032640351056putative cell division proteinQuickGO ontologyBLASTP
32640323264778747hypothetical proteinBLASTP
32648503265431582hypothetical proteinBLASTP
326551332666551143hypothetical proteinBLASTP
32669943267356363ribonuclease P protein componentQuickGO ontologyBLASTP
3267378326752114450S ribosomal protein L34QuickGO ontologyBLASTP