Pre_GI Gene

Some Help

Host: NC_011896 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011896:3040500 Mycobacterium leprae Br4923, complete genome

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
30491623049458297hypothetical proteinBLASTP
30530903053578489putative oxidoreductaseQuickGO ontologyBLASTP
30544553054745291hypothetical proteinBLASTP
305509730569321836acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
305735430587271374acetyl-CoA C-acetyltransferaseQuickGO ontologyBLASTP
305883230601961365putative oxidoreductaseQuickGO ontologyBLASTP
30612373062139903hypothetical proteinBLASTP