Pre_GI Gene

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Host: NC_011896 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011896:2775000 Mycobacterium leprae Br4923, complete genome

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
277940227816002199putative regulatory proteinQuickGO ontologyBLASTP
27869942787899906hypothetical proteinBLASTP
278819827892081011hypothetical proteinBLASTP
278939927906641266putative glycosyl transferaseQuickGO ontologyBLASTP
279081027920811272hypothetical proteinBLASTP
27921302792960831putative antibiotic resistance membrane proteinQuickGO ontologyBLASTP
27929572793823867putative antibiotic resistance membrane proteinQuickGO ontologyBLASTP
27938202794815996putative antibiotic resistance efflux proteinQuickGO ontologyBLASTP