Pre_GI Gene

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Host: NC_011896 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011896:2571232 Mycobacterium leprae Br4923, complete genome

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
257123225724431212putative beta-ketoadipyl CoA thiolaseQuickGO ontologyBLASTP
257588725775961710pyruvate or indolepyruvate decarboxylaseQuickGO ontologyBLASTP
25791312579355225hypothetical proteinBLASTP
25831692583525357hypothetical proteinBLASTP
25860722586476405cytidine deaminaseQuickGO ontologyBLASTP
25881182588375258hypothetical proteinBLASTP
25885282589481954putative uridine phosphorylaseQuickGO ontologyBLASTP
25897222589973252hypothetical proteinBLASTP
2594614259469077tRNA-AspQuickGO ontologyBLASTP
2594917259498973tRNA-LysQuickGO ontologyBLASTP