Pre_GI Gene

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Host: NC_011896 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011896:2539908 Mycobacterium leprae Br4923, complete genome

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
25399082540663756hypothetical proteinBLASTP
25419102542341432putative MarR-family proteinQuickGO ontologyBLASTP
25425452542820276hypothetical proteinBLASTP
25429322543741810hypothetical proteinBLASTP
254385125455901740hypothetical proteinBLASTP
25455982546086489hypothetical proteinBLASTP
25519362552346411putative cold shock proteinQuickGO ontologyBLASTP
25546702555194525hypothetical proteinBLASTP
25566412556865225hypothetical 101 kda proteinQuickGO ontologyBLASTP
255696325592242262putative DNA-binding proteinQuickGO ontologyBLASTP
255926125609101650putative DNA helicaseQuickGO ontologyBLASTP
25610222561414393hypothetical proteinBLASTP