Pre_GI Gene

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Host: NC_011896 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011896:1380000 Mycobacterium leprae Br4923, complete genome

Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
13803401380627288hypothetical proteinBLASTP
13806791380981303hypothetical proteinBLASTP
138104413822971254PPE-family proteinQuickGO ontologyBLASTP
13823541382653300hypothetical proteinBLASTP
13868041387106303hypothetical proteinBLASTP
13906231390883261hypothetical proteinBLASTP
13925211392904384hypothetical proteinBLASTP
13953191396038720hypothetical proteinBLASTP
139665014058809231fatty acid synthaseQuickGO ontologyBLASTP