Pre_GI Gene

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Host: NC_011725 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011725:4799905 Bacillus cereus B4264 chromosome, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain was isolated in 1969 from a case of fatal pneumonia in a male patient. B. cereus B4264 was cultured from the blood and the pleural fluid. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
479990548010081104pyridoxal phosphate-dependent enzymeQuickGO ontologyBLASTP
480098648020861101dihydroorotaseQuickGO ontologyBLASTP
48024324802722291hypothetical proteinBLASTP
48027434803345603hypothetical proteinBLASTP
48038794804739861D-alanyl-D-alanine carboxypeptidaseQuickGO ontologyBLASTP
480482248059281107sensor histidine kinaseQuickGO ontologyBLASTP
48059214806619699DNA-binding response regulatorQuickGO ontologyBLASTP
480686048079661107N-acylamino acid racemaseQuickGO ontologyBLASTP
480796748094151449O-succinylbenzoic acid--CoA ligaseQuickGO ontologyBLASTP
48095824809752171hypothetical protein
48097494810567819naphthoate synthaseQuickGO ontologyBLASTP
48106364811448813SHCHC synthaseQuickGO ontologyBLASTP
4811445481319917552-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthaseQuickGO ontologyBLASTP
481319648145901395menaquinone-specific isochorismate synthaseQuickGO ontologyBLASTP
4814785481573895414-dihydroxy-2-naphthoate octaprenyltransferaseQuickGO ontologyBLASTP
48158484816579732DNA binding protein DksATraR familyQuickGO ontologyBLASTP
48166244816824201cold shock protein CspDQuickGO ontologyBLASTP
48172164817998783hypothetical proteinBLASTP
48182134818362150hypothetical proteinBLASTP
48187004819422723lipaseQuickGO ontologyBLASTP
48194994819633135hypothetical proteinBLASTP
481973748221452409glycogen phosphorylaseQuickGO ontologyBLASTP