Pre_GI Gene

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Host: NC_011725 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011725:4159000 Bacillus cereus B4264 chromosome, complete genome

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain was isolated in 1969 from a case of fatal pneumonia in a male patient. B. cereus B4264 was cultured from the blood and the pleural fluid. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
41590814159545465NUDIX family hydrolaseQuickGO ontologyBLASTP
41596164160320705hypothetical proteinBLASTP
416042841616061179FtsWRodASpoVE family cell division proteinQuickGO ontologyBLASTP
416194941632681320branched-chain alpha-keto acid dehydrogenase subunit E2QuickGO ontologyBLASTP
416328441642679843-methyl-2-oxobutanoate dehydrogenaseQuickGO ontologyBLASTP
4164281416528210023-methyl-2-oxobutanoate dehydrogenaseQuickGO ontologyBLASTP
416531041667311422dihydrolipoamide dehydrogenaseQuickGO ontologyBLASTP
416673641678391104butyrate kinaseQuickGO ontologyBLASTP
416792741690271101leucine dehydrogenaseQuickGO ontologyBLASTP
41690624169961900phosphate butyryltransferaseQuickGO ontologyBLASTP
417015741722712115sensory box sigma-54 dependent DNA-binding response regulatorQuickGO ontologyBLASTP
41723674172600234hypothetical proteinBLASTP
41726504173378729glycerophosphoryl diester phosphodiesteraseQuickGO ontologyBLASTP
41734294173575147hypothetical proteinBLASTP
41738174174380564hypothetical proteinBLASTP
41746334175463831stage 0 sporulation protein AQuickGO ontologyBLASTP
417571841770071290stage IV sporulation protein BQuickGO ontologyBLASTP
417713541788741740DNA repair protein RecNQuickGO ontologyBLASTP
41791394179588450arginine repressor ArgRQuickGO ontologyBLASTP
41797314180570840hemolysin AQuickGO ontologyBLASTP