Pre_GI Gene

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Host: NC_011655 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011655:230631 Bacillus cereus AH187 plasmid pAH187_270, complete sequence

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain was isolated from the vomit of a person having eaten cooked rice by the Public Health Laboratory Service (PHLS), London, UK. The isolate was associated with an emetic outbreak in 1972. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
2306312386768046linear gramicidin synthetase subunit BQuickGO ontologyBLASTP
23869024881410125linear gramicidin synthetase subunit DQuickGO ontologyBLASTP
248831249544714type II thioesterase CesTQuickGO ontologyBLASTP