Pre_GI Gene

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Host: NC_011601 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011601:1466496 Escherichia coli O127:H6 str. E2348/69 chromosome, complete genome

Host Lineage: Escherichia coli; Escherichia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Enteropathogenic Escherichia coli (EPEC) is an important cause of fatal infant diarrhea. EPEC induces diarrhea by attaching and effacing to host cells in the small intestine, inducing cytoskeletal rearrangements that result in pedastel formation, and then by introducing toxins into the host cell. This organism was named for its discoverer, Theodore Escherich, and is one of the premier model organisms used in the study of bacterial genetics, physiology, and biochemistry. This enteric organism is typically present in the lower intestine of humans, where it is the dominant facultative anaerobe present, but it is only one minor constituent of the complete intestinal microflora. E. coli, is capable of causing various diseases in its host, especially when they acquire virulence traits. E. coli can cause urinary tract infections, neonatal meningitis, and many different intestinal diseases, usually by attaching to the host cell and introducing toxins that disrupt normal cellular processes.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
146649614699693474host specificity proteinQuickGO ontologyBLASTP
14700371470636600outer membrane precursor LomQuickGO ontologyBLASTP
147078814720651278side tail fiber proteinQuickGO ontologyBLASTP
14720671472336270hypothetical proteinBLASTP
14725571473099543hypothetical proteinBLASTP
147358114749031323T3SS secreted effector NleAEspI-like proteinQuickGO ontologyBLASTP
14767241477635912T3SS secreted effector NleH-like proteinQuickGO ontologyBLASTP
14777011478270570T3SS secreted effector NleF-like proteinQuickGO ontologyBLASTP
14808071481265459transposase of IS200CQuickGO ontologyBLASTP
148155714829301374transposase of ISEc13QuickGO ontologyBLASTP
14830061483812807tryptophan synthase subunit alphaQuickGO ontologyBLASTP
148381214850051194tryptophan synthase subunit betaQuickGO ontologyBLASTP
148501714863751359bifunctional indole-3-glycerol phosphate synthasephosphoribosylanthranilate isomeraseQuickGO ontologyBLASTP
148637914879741596bifunctional glutamine amidotransferaseanthranilate phosphoribosyltransferaseQuickGO ontologyBLASTP
148797414895301557anthranilate synthase component IQuickGO ontologyBLASTP