Pre_GI Gene

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Host: NC_011247 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011247:55382 Borrelia duttonii Ly plasmid pl165, complete sequence

Host Lineage: Borrelia duttonii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia duttonii Ly was isolated from a 2-year-old girl with tick-borne relapsing fever in Tanzania. Borrelia duttonii is the causative agent of tick-borne relapsing fever in east Africa. This disease is endemic in much of east Africa and is one of the top 10 diseases associated with deaths in children under the age of five. This disease is transmitted by the bite of the soft-bodied tick Ornithodoros moubata. Ticks become infected with Borrelia duttonii while feeding on an infected rodent. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Humans become exposed to the infected ticks through contact with rodents or rodent nests. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
5538256266885hypothetical proteinBLASTP
5655457498945hypothetical proteinBLASTP
5809858925828hypothetical proteinBLASTP
6052761327801hypothetical proteinBLASTP
6160962481873hypothetical proteinBLASTP
6269863471774putative lipoproteinQuickGO ontologyBLASTP
6382864724897putative lipoproteinQuickGO ontologyBLASTP
6487865750873hypothetical proteinBLASTP
6596866765798putative lipoproteinQuickGO ontologyBLASTP
6690167689789putative lipoproteinQuickGO ontologyBLASTP
6771768493777putative lipoproteinQuickGO ontologyBLASTP
6851269288777putative lipoproteinQuickGO ontologyBLASTP
70138712351098hypothetical proteinBLASTP
7157572291717putative lipoproteinQuickGO ontologyBLASTP
7252173261741hypothetical proteinBLASTP
73495745561062putative viral A-type inclusion protein repeatQuickGO ontologyBLASTP
7489475754861hypothetical protein
7578276699918hypothetical protein
7679977404606hypothetical proteinBLASTP
7757478182609hypothetical proteinBLASTP