Pre_GI Gene

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Host: NC_011247 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011247:110545 Borrelia duttonii Ly plasmid pl165, complete sequence

Host Lineage: Borrelia duttonii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: Borrelia duttonii Ly was isolated from a 2-year-old girl with tick-borne relapsing fever in Tanzania. Borrelia duttonii is the causative agent of tick-borne relapsing fever in east Africa. This disease is endemic in much of east Africa and is one of the top 10 diseases associated with deaths in children under the age of five. This disease is transmitted by the bite of the soft-bodied tick Ornithodoros moubata. Ticks become infected with Borrelia duttonii while feeding on an infected rodent. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Humans become exposed to the infected ticks through contact with rodents or rodent nests. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1126241140391416lipoproteinQuickGO ontologyBLASTP
1141841156171434putative lipoproteinQuickGO ontologyBLASTP
1171061193792274hypothetical protein
119569120555987hypothetical protein
120749121465717hypothetical protein
121512122072561hypothetical protein
122308123123816p23-like cell envelope proteinQuickGO ontologyBLASTP
123387124187801p23-like cell envelope proteinQuickGO ontologyBLASTP
124709125239531hypothetical protein
1256171269691353bsr proteinQuickGO ontologyBLASTP
126972127523552hypothetical protein
128307128858552PF49 plasmid partition proteinQuickGO ontologyBLASTP
128909129664756PF32 plasmid partition proteinQuickGO ontologyBLASTP
129640130203564plasmid partitioning associated protein-1QuickGO ontologyBLASTP