Pre_GI Gene

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Host: NC_011205 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011205:3078732 Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This is a bovine-adapted serovar that is genetically related to S. Enteritidis that lives in the bovine intestinal tract and can causes disease in humans. While rare in incidence, S. dublin infection classically produces a syndrome of sustained bacteremia with fever, resulting in high morbidity and mortality. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
30780683078742675surface presentation of antigens protein SpaPQuickGO ontologyBLASTP
30787323079643912surface presentation of antigens protein SpaOQuickGO ontologyBLASTP
307964330806531011antigen presentation protein SpaNQuickGO ontologyBLASTP
30806533081096444surface presentation of antigens protein SpaMQuickGO ontologyBLASTP
308107430823691296ATP synthase SpaLQuickGO ontologyBLASTP
30823663082773408surface presentation of antigens protein SpaKQuickGO ontologyBLASTP
308279730848542058invasion protein InvAQuickGO ontologyBLASTP
308487930859971119invasion protein InvEQuickGO ontologyBLASTP
308599430875381545type III secretion outer membrane pore YscCHrcC familyQuickGO ontologyBLASTP
30876793088428750invasion proteinQuickGO ontologyBLASTP
30887853089228444cell adheranceinvasion proteinQuickGO ontologyBLASTP
30900893090370282ABC transporterQuickGO ontologyBLASTP
30903703090894525GNAT family acetyltransferaseQuickGO ontologyBLASTP
30916093092265657serinethreonine-specific protein phosphatase 2QuickGO ontologyBLASTP
30924373092931495hypothetical proteinBLASTP
30929583093626669hypothetical proteinBLASTP
30940493094171123hypothetical proteinBLASTP
309477030973372568DNA mismatch repair protein MutSQuickGO ontologyBLASTP
30973933097773381hypothetical proteinBLASTP
309777030989781209major facilitator family transporterQuickGO ontologyBLASTP