Pre_GI Gene

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Host: NC_011205 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011205:1852665 Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This is a bovine-adapted serovar that is genetically related to S. Enteritidis that lives in the bovine intestinal tract and can causes disease in humans. While rare in incidence, S. dublin infection classically produces a syndrome of sustained bacteremia with fever, resulting in high morbidity and mortality. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
185266518538131149cyclopropane fatty acyl phospholipid synthaseQuickGO ontologyBLASTP
18538551854496642riboflavin synthase subunit alphaQuickGO ontologyBLASTP
185471318560861374multidrug efflux proteinQuickGO ontologyBLASTP
185655918576171059secretion system apparatus protein SsaUQuickGO ontologyBLASTP
18576141858393780type III secretion apparatus protein SpaRYscTHrcTQuickGO ontologyBLASTP
18583941858507114secretion system apparatus protein SsaSQuickGO ontologyBLASTP
18586571859304648type III secretion system proteinQuickGO ontologyBLASTP
18593721860340969type III secretion system proteinQuickGO ontologyBLASTP
18603211860662342secretion system apparatus protein SsaPQuickGO ontologyBLASTP
18606761861053378secretion system apparatus SsaOQuickGO ontologyBLASTP
186105618623871332type III secretion system ATPaseQuickGO ontologyBLASTP
186234718643922046secretion system apparatus protein SsaVQuickGO ontologyBLASTP
18643771864745369secretion system apparatus protein SsaMQuickGO ontologyBLASTP
18648031865795993secretion system apparatus protein SsaLQuickGO ontologyBLASTP
18664561866728273secretion system apparatusQuickGO ontologyBLASTP
18670221867771750type III secretion apparatus lipoprotein YscJHrcJ familyQuickGO ontologyBLASTP
18677681868031264type III secretion system apparatus proteinQuickGO ontologyBLASTP
18680281868318291SsaH family type III secretion system proteinQuickGO ontologyBLASTP
18682961868511216type III secretion apparatus needle proteinQuickGO ontologyBLASTP
18686051869294690secreted effector proteinQuickGO ontologyBLASTP
18692911870073783secreted effector proteinQuickGO ontologyBLASTP
18700891870517429type III secretion low calcium response chaperone LcrHSycDQuickGO ontologyBLASTP
18705751870730156secreted effector proteinQuickGO ontologyBLASTP
18709941871497504translocation machinery componentQuickGO ontologyBLASTP
187159718730511455translocation machinery componentQuickGO ontologyBLASTP
18730541873569516type III secretion low calcium response chaperone LcrHSycDQuickGO ontologyBLASTP
18735241874114591secretion system effector SseBQuickGO ontologyBLASTP
18746501874883234YseE family type III secretion system proteinQuickGO ontologyBLASTP
187490018760991200type III secretion apparatus protein YscDHrpQ familyQuickGO ontologyBLASTP
187609218775851494type III secretion outer membrane pore YscCHrcC familyQuickGO ontologyBLASTP
187838918811512763secretion system regulatorSensor componentQuickGO ontologyBLASTP
18811821881820639hypothetical proteinBLASTP
18828981883857960inner membrane proteinQuickGO ontologyBLASTP
18839791884191213hypothetical proteinBLASTP
18842891884909621response regulatorQuickGO ontologyBLASTP
188488418866321749sensor-kinaseQuickGO ontologyBLASTP
18868441887578735tetrathionate reductase subunit BQuickGO ontologyBLASTP
188757918886011023tetrathionate reductase complex subunit CQuickGO ontologyBLASTP
188859418916563063molydopterin dinucleotide domain-containing proteinQuickGO ontologyBLASTP