Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:924326 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
9243269258641539glutathione-binding protein GsiBQuickGO ontologyBLASTP
925925926845921inner membrane ABC transporter permease protein YddRQuickGO ontologyBLASTP
926848927759912glutathione transport system permease protein GsiDQuickGO ontologyBLASTP
9278509291751326hypothetical proteinBLASTP
929202929336135hypothetical proteinBLASTP
929406929789384biofilm regulator BssRQuickGO ontologyBLASTP
930240930404165hypothetical proteinBLASTP
930503931018516citrate lyaseQuickGO ontologyBLASTP
931041931790750electron transfer flavoprotein subunit betaQuickGO ontologyBLASTP
931801932748948electron transfer flavoprotein subunit alphaQuickGO ontologyBLASTP
9330429342051164acyl-CoA dehydrogenase domain proteinQuickGO ontologyBLASTP
9346549363391686electron transfer flavoprotein-ubiquinone oxidoreductaseQuickGO ontologyBLASTP
936345937235891transcriptional regulator LysR familyQuickGO ontologyBLASTP
937500937925426citrate transporter family proteinQuickGO ontologyBLASTP
938960939586627glutathione S-transferase family proteinQuickGO ontologyBLASTP
9398309410321203D-alanyl-D-alanine carboxypeptidase DacCQuickGO ontologyBLASTP
941078941836759deoxyribose operon repressorQuickGO ontologyBLASTP
941908942582675putative undecaprenyl-diphosphatase YbjGQuickGO ontologyBLASTP
9428299440611233multidrug resistance protein MdtMQuickGO ontologyBLASTP
944115944930816phosphatase YbjIQuickGO ontologyBLASTP
9449279461381212inner membrane protein YbjJQuickGO ontologyBLASTP
946306946926621transcriptional regulator TetR familyQuickGO ontologyBLASTP