Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:819103 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
8191038202811179protein TolAQuickGO ontologyBLASTP
8204028216971296tol-Pal system beta propeller repeat protein TolBQuickGO ontologyBLASTP
821732822256525peptidoglycan-associated lipoproteinQuickGO ontologyBLASTP
822266823054789tetratricopeptide TPR_2 repeat proteinQuickGO ontologyBLASTP
82351082358576tRNA-LysQuickGO ontologyBLASTP
82397082404576tRNA-LysQuickGO ontologyBLASTP
8245868256291044quinolinate synthetase complex A subunitQuickGO ontologyBLASTP
825654826373720PnuC proteinQuickGO ontologyBLASTP
826370827308939zinc transporter ZitBQuickGO ontologyBLASTP
827419827805387putative homeobox proteinQuickGO ontologyBLASTP
82812582917710533-deoxy-7-phosphoheptulonate synthase Phe-sensitiveQuickGO ontologyBLASTP
829271829816546fumarate hydratase I beta subunitQuickGO ontologyBLASTP
829831830676846fumarate hydrataseQuickGO ontologyBLASTP
830806831696891transcriptional regulatorQuickGO ontologyBLASTP
831697832623927transcriptional regulatorQuickGO ontologyBLASTP
8329038341711269anion transporterQuickGO ontologyBLASTP
834260834466207oxaloacetate decarboxylase gamma chain 2QuickGO ontologyBLASTP
8344828362571776oxaloacetate decarboxylase alpha subunitQuickGO ontologyBLASTP
8362708375711302oxaloacetate decarboxylase beta chainQuickGO ontologyBLASTP
837690838388699putative cytoplasmic proteinQuickGO ontologyBLASTP
8387688398471080ABC transporter permeaseQuickGO ontologyBLASTP
839847840623777ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
84071484146675323-bisphosphoglycerate-dependent phosphoglycerate mutaseQuickGO ontologyBLASTP
8416908427301041galactose mutarotaseQuickGO ontologyBLASTP
8427248438721149galactokinaseQuickGO ontologyBLASTP