Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:780850 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
7808507823311482inner membrane transporter YbgHQuickGO ontologyBLASTP
782660783403744hypothetical proteinBLASTP
783419784075657hypothetical proteinBLASTP
784069785001933allophanate hydrolase subunit 2QuickGO ontologyBLASTP
784991785725735protein YbgLQuickGO ontologyBLASTP
786049786189141hypothetical proteinBLASTP
786239786805567HbiFQuickGO ontologyBLASTP
787454787600147putative inner membrane proteinQuickGO ontologyBLASTP
787644788342699hypothetical proteinBLASTP
7886287897791152UDP-galactopyranose mutaseQuickGO ontologyBLASTP
789779790672894putative glycosyl transferaseQuickGO ontologyBLASTP
7906857918181134galactosyltransferaseQuickGO ontologyBLASTP
791947792717771O-antigen export system permease proteinQuickGO ontologyBLASTP
792721793431711ABC transporter domain proteinQuickGO ontologyBLASTP
7935257953031779putative glycosyltransferase cell wall biogenesisQuickGO ontologyBLASTP
795553796329777hypothetical proteinBLASTP
7963337982821950putative glycosyl transferaseQuickGO ontologyBLASTP
798350798487138putative cytoplasmic proteinQuickGO ontologyBLASTP
798536799327792endonuclease VIIIQuickGO ontologyBLASTP
7993828004281047protein AbrBQuickGO ontologyBLASTP
8005658018481284citrate Si-synthaseQuickGO ontologyBLASTP
802588802992405succinate dehydrogenase cytochrome b556 subunitQuickGO ontologyBLASTP
802986803333348succinate dehydrogenase hydrophobic membrane anchor proteinQuickGO ontologyBLASTP
8033338050991767succinate dehydrogenase flavoprotein subunitQuickGO ontologyBLASTP
805113805832720succinate dehydrogenase iron-sulfur subunitQuickGO ontologyBLASTP
8063568091572802oxoglutarate dehydrogenase succinyl-transferring E1 componentQuickGO ontologyBLASTP