Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:610428 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
6104286130402613fimbrial usher proteinQuickGO ontologyBLASTP
6130556140621008mannose binding protein FimHQuickGO ontologyBLASTP
614072614590519major fimbrial subunitQuickGO ontologyBLASTP
614636615268633fimbriae Z proteinQuickGO ontologyBLASTP
615872616594723fimbriae Y proteinQuickGO ontologyBLASTP
616613616834222hypothetical proteinBLASTP
617086617682597fimbriae W proteinQuickGO ontologyBLASTP
6190446208551812hypothetical proteinBLASTP
620852621772921glycosyl transferaseQuickGO ontologyBLASTP
621769622131363bactoprenol-linked glucose translocaseQuickGO ontologyBLASTP
622863622985123hypothetical protein
623427623684258cation efflux system protein CusAQuickGO ontologyBLASTP
623665624519855transcriptional regulator AraC family proteinQuickGO ontologyBLASTP
6247356260601326probable pyridine nucleotide-disulfide oxidoreductase YkgCQuickGO ontologyBLASTP
626111626233123hypothetical proteinBLASTP
626217626453237hypothetical proteinBLASTP
626466627026561protein of unknown function superfamilyQuickGO ontologyBLASTP
6271056282801176heat shock protein DnaJ domain proteinQuickGO ontologyBLASTP
6286066300001395phenylalanine-specific permeaseQuickGO ontologyBLASTP
6300426312891248transporter small conductance mechanosensitive ion channelQuickGO ontologyBLASTP
631319631501183hypothetical proteinBLASTP