Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:4177443 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
417744341788521410nitrogen regulation protein NRQuickGO ontologyBLASTP
417886141799101050nitrogen regulation protein NRQuickGO ontologyBLASTP
418018541815941410glutamine synthetaseQuickGO ontologyBLASTP
418197041837931824GTP-binding protein TypAQuickGO ontologyBLASTP
41838484184027180hypothetical protein
41841844184876693porin OmpLQuickGO ontologyBLASTP
418494441863621419sugar Glycoside-Pentoside-Hexuronide transporterQuickGO ontologyBLASTP
418640841877901383inner membrane symporter YihPQuickGO ontologyBLASTP
418783641898722037alpha-glucosidase YihQQuickGO ontologyBLASTP
41899964190871876putative domain of unknown functionQuickGO ontologyBLASTP
41909604191847888aldose-1-epimerase family proteinQuickGO ontologyBLASTP
419193441931751242N-acylglucosamine 2-epimeraseQuickGO ontologyBLASTP
41931914194069879deoxyribose-phosphate aldolaseQuickGO ontologyBLASTP
419409241949888973-hydroxyisobutyrate dehydrogenase familyQuickGO ontologyBLASTP
41949764195095120hypothetical protein
41951534196049897kinase PfkB familyQuickGO ontologyBLASTP
41960834196886804glycerol-3-phosphate regulon repressorQuickGO ontologyBLASTP
41970774197676600phosphatase YihXQuickGO ontologyBLASTP
41976704198542873tRNA-processing ribonuclease BNQuickGO ontologyBLASTP
41985394198976438D-tyrosyl-tRNATyr deacylaseQuickGO ontologyBLASTP
41989734199962990acetyltransferase gnat familyQuickGO ontologyBLASTP
41999774200405429Sea41QuickGO ontologyBLASTP