Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:3976441 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
39764413976971531f165QuickGO ontologyBLASTP
39769683977330363inner membrane protein YidGQuickGO ontologyBLASTP
39773203977667348inner membrane protein YidHQuickGO ontologyBLASTP
39776873977821135hypothetical proteinBLASTP
39778213977949129hypothetical proteinBLASTP
397811139797721662putative potassium uptake protein TrkAQuickGO ontologyBLASTP
39799613980389429small heat shock protein IbpBQuickGO ontologyBLASTP
39804993980918420small heat shock protein IbpAQuickGO ontologyBLASTP
39811763981295120hypothetical proteinBLASTP
39812943981554261conserved outer membrane proteinQuickGO ontologyBLASTP
398290439839471044cytochrome c-type biogenesis protein H2QuickGO ontologyBLASTP
39839443984501558thioldisulfide interChange protein DsbEQuickGO ontologyBLASTP
398449839864291932cytochrome c-type biogenesis protein CcmFQuickGO ontologyBLASTP
39864263986905480ABC superfamilyQuickGO ontologyBLASTP
39869023987114213hypothetical proteinBLASTP
39871113987857747ABC superfamilyQuickGO ontologyBLASTP
39879003988559660heme exporter protein CcmBQuickGO ontologyBLASTP
39885563989182627heme ABC exporter ATP-binding protein CcmAQuickGO ontologyBLASTP
398917939905791401cytochrome-c peroxidaseQuickGO ontologyBLASTP
39907693991401633chaperone protein TorDQuickGO ontologyBLASTP
399139439939462553trimethylamine-N-oxide reductase TorAQuickGO ontologyBLASTP
399393639951201185trimethylamine-N-oxide reductase c-type cytochrome TorCQuickGO ontologyBLASTP
39952143995942729TorCAD operon transcriptional regulatory protein TorRQuickGO ontologyBLASTP
399591539969551041tmao reductase system periplasmic protein tortQuickGO ontologyBLASTP
39969803997096117hypothetical proteinBLASTP
399708339997702688TMAO reductase sytem sensor TorSQuickGO ontologyBLASTP