Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:3875320 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
387532038763451026L-threonine 3-dehydrogenaseQuickGO ontologyBLASTP
3876355387755111972-amino-3-ketobutyrate coenzyme A ligaseQuickGO ontologyBLASTP
38777543878686933ADP-glyceromanno-heptose 6-epimeraseQuickGO ontologyBLASTP
387868938797351047lipopolysaccharide heptosyltransferase IIQuickGO ontologyBLASTP
38797353880688954lipopolysaccharide heptosyltransferase IQuickGO ontologyBLASTP
388072838819421215O-antigen ligaseQuickGO ontologyBLASTP
388199938831441146lipopolysaccharide 12-N-acetylglucosaminetransferaseQuickGO ontologyBLASTP
38832443884053810lipopolysaccharide core biosynthesis protein RfaZQuickGO ontologyBLASTP
38842033884901699lipopolysaccharide core biosynthesis protein RfaYQuickGO ontologyBLASTP
388492438859341011lipopolysaccharide 12-glucosyltransferaseQuickGO ontologyBLASTP
388595238869651014lipopolysaccharide 13-galactosyltransferaseQuickGO ontologyBLASTP
388697138880501080lipopolysaccharide 16-galactosyltransferaseQuickGO ontologyBLASTP
38880643889044981WaaSQuickGO ontologyBLASTP
38891003889897798lipopolysaccharide core biosynthesis proteinQuickGO ontologyBLASTP
388989038910141125lipopolysaccharide core biosynthesis protein RfaGQuickGO ontologyBLASTP
389101138920811071putative lipopolysaccharide heptosyltransferase IIIQuickGO ontologyBLASTP
3892489389376612783-deoxy-D-manno-octulosonic-acid transferaseQuickGO ontologyBLASTP
38937753894254480pantetheine-phosphate adenylyltransferaseQuickGO ontologyBLASTP
38942823895091810formamidopyrimidine-DNA glycosylaseQuickGO ontologyBLASTP
38951893895356168ribosomal protein L33QuickGO ontologyBLASTP
38953773895613237ribosomal protein L28QuickGO ontologyBLASTP
38958313896496666DNA repair protein RadCQuickGO ontologyBLASTP
38978703898328459dUTP diphosphataseQuickGO ontologyBLASTP
38984363899032597transcriptional regulator domain protein TetR familyQuickGO ontologyBLASTP
38991103899751642orotate phosphoribosyltransferaseQuickGO ontologyBLASTP
38998293900545717ribonuclease PHQuickGO ontologyBLASTP