Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:383441 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
383441384199759fimbrial chaperone proteinQuickGO ontologyBLASTP
3841653854901326putative fimbrial usherQuickGO ontologyBLASTP
3854953880562562outer membrane fimbrial usher proteinQuickGO ontologyBLASTP
388040388969930fimbrial chaperone proteinQuickGO ontologyBLASTP
388781388927147hypothetical protein
390063390797735putative transmembrane regulatorQuickGO ontologyBLASTP
3915943931441551putative rtn proteinQuickGO ontologyBLASTP
393244393987744putative response regulatorQuickGO ontologyBLASTP
393960394448489putative inner membrane proteinQuickGO ontologyBLASTP
394848395372525attachment invasion locus proteinQuickGO ontologyBLASTP
395516396157642putative response regulatorQuickGO ontologyBLASTP
396426396809384cytochrome c type biogenesis protein CycHQuickGO ontologyBLASTP
3968793983361458outer membrane protein OprMQuickGO ontologyBLASTP
3983534015203168OqxBQuickGO ontologyBLASTP
4015174027431227putative auxiliary transport protein membrane fusion protein MFP familyQuickGO ontologyBLASTP
4030204053082289copper-translocating P-type ATPaseQuickGO ontologyBLASTP
405320405784465CuI-responsive transcriptional regulatorQuickGO ontologyBLASTP
405862406056195hypothetical proteinBLASTP