Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:333121 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
3331213353102190Rhs-family proteinQuickGO ontologyBLASTP
335334335780447hypothetical proteinBLASTP
3357993398784080Rhs-family proteinQuickGO ontologyBLASTP
339872340318447putative cytoplasmic proteinQuickGO ontologyBLASTP
340704340844141hypothetical proteinBLASTP
340837341319483phosphotriesteraseQuickGO ontologyBLASTP
341372341647276hypothetical proteinBLASTP
341709341828120hypothetical proteinBLASTP
342275342415141rhs core protein with extensionQuickGO ontologyBLASTP
343087343554468hypothetical proteinBLASTP
344172344330159hypothetical proteinBLASTP
344662344802141hypothetical proteinBLASTP
346035346166132hypothetical protein
346673346792120hypothetical protein
346938347234297hypothetical proteinBLASTP
347309348049741periplasmic fimbrial chaperone proteinQuickGO ontologyBLASTP
3480733505832511outer-membrane fimbrial usher proteinQuickGO ontologyBLASTP
350605351075471putative fimbrial structural subunitQuickGO ontologyBLASTP
351483352304822polysaccharide deacetylase family proteinQuickGO ontologyBLASTP
352787352918132TnpAQuickGO ontologyBLASTP
353121354068948LysR-family transcriptional regulator SinRQuickGO ontologyBLASTP
354188354403216putative cytoplasmic proteinQuickGO ontologyBLASTP
354407355126720putative outer membrane adhesinQuickGO ontologyBLASTP
355151355279129hypothetical proteinBLASTP
355457355864408periplasmic proteinQuickGO ontologyBLASTP
356174356941768hydrolase YafVQuickGO ontologyBLASTP