Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:2897977 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
289797728992211245enterochelin esteraseQuickGO ontologyBLASTP
28992532900188936IroEQuickGO ontologyBLASTP
290023029024042175TonB dependent outer membrane siderophore receptor proteinQuickGO ontologyBLASTP
290344229045421101effector protein pipB2QuickGO ontologyBLASTP
29050122905941930virulence proteinQuickGO ontologyBLASTP
29060412906238198hypothetical proteinBLASTP
29062352907131897Mig-14QuickGO ontologyBLASTP
29076472907760114putative inner membrane proteinQuickGO ontologyBLASTP
290785329088661014high-affinity nickel transport proteinQuickGO ontologyBLASTP
290899929104141416tricarboxylic transport regulatory proteinQuickGO ontologyBLASTP
29104012911075675transcriptional regulatory protein TctDQuickGO ontologyBLASTP
29112302912207978tricarboxylic transportQuickGO ontologyBLASTP
29122222912653432tricarboxylic transportQuickGO ontologyBLASTP
291266429141781515integral membrane proteinQuickGO ontologyBLASTP
29143422914455114hypothetical proteinBLASTP
29144822915459978protein CsiDQuickGO ontologyBLASTP
291548529167531269putative FAD dependent oxidoreductaseQuickGO ontologyBLASTP
291677529182231449succinate-semialdehyde dehydrogenase NADPQuickGO ontologyBLASTP
2918238291952112844-aminobutyrate transaminaseQuickGO ontologyBLASTP