Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:2870428 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
28704282870697270zinc-finger proteinQuickGO ontologyBLASTP
28706712870868198hypothetical proteinBLASTP
287100228730232022replication gene A proteinQuickGO ontologyBLASTP
28730202873853834retron EC67 DNA adenine methylaseQuickGO ontologyBLASTP
28738432874172330gp91QuickGO ontologyBLASTP
28741632874393231hypothetical proteinBLASTP
28744612874862402hypothetical proteinBLASTP
28749352875153219hypothetical proteinBLASTP
28752772875504228hypothetical proteinBLASTP
28755142876017504regulatory protein CII bacteriophage 186QuickGO ontologyBLASTP
28760552876258204hypothetical protein
28766832876970288repressor proteinQuickGO ontologyBLASTP
287697028779801011phage integraseQuickGO ontologyBLASTP
287832628795191194phage integrase family proteinQuickGO ontologyBLASTP
287953028806451116hypothetical proteinBLASTP
288063328824021770domain of unknown function proteinQuickGO ontologyBLASTP
28826092883175567phage polarity suppression proteinQuickGO ontologyBLASTP
28831922883437246phage transcriptional activator OgrdeltaQuickGO ontologyBLASTP
28834342884129696glycoprotein 3QuickGO ontologyBLASTP
28840972884273177hypothetical proteinBLASTP
28842432884389147hypothetical proteinBLASTP
28847122884978267phage DNA binding proteinQuickGO ontologyBLASTP
28853382885532195phage immunity repressor proteinQuickGO ontologyBLASTP
28855772885756180hypothetical proteinBLASTP
28857532886073321hypothetical P4 phage proteinQuickGO ontologyBLASTP
288608828884212334bacteriophage P4 DNA primaseQuickGO ontologyBLASTP
28892622889732471repressor of phase 1 flagellin geneQuickGO ontologyBLASTP
288986928913891521flagellinQuickGO ontologyBLASTP
28914812892047567DNA-invertase hinQuickGO ontologyBLASTP
289301528941301116IroBQuickGO ontologyBLASTP