Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:2789744 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
278974427907811038RNA methyltransferase TrmH familyQuickGO ontologyBLASTP
27909852791404420putative thioredoxinQuickGO ontologyBLASTP
27914772792157681DTW domain proteinQuickGO ontologyBLASTP
279221127948712661CoA binding domainacetyltransferase domain proteinQuickGO ontologyBLASTP
279498627963411356CDP-diacylglycerol--serine O-phosphatidyltransferaseQuickGO ontologyBLASTP
27963862796709324hypothetical proteinBLASTP
279670627980071302alpha-ketoglutarate permeaseQuickGO ontologyBLASTP
27981112798566456putative cytoplasmic proteinQuickGO ontologyBLASTP
27988142798945132hypothetical protein
279899127991061165S ribosomal RNAQuickGO ontologyBLASTP
280464128072142574ATP-dependent chaperone protein ClpBQuickGO ontologyBLASTP
28073442808075732hypothetical proteinBLASTP
28080722809052981ribosomal large subunit pseudouridine synthase DQuickGO ontologyBLASTP
28091842809921738outer membrane assembly lipoprotein YfiOQuickGO ontologyBLASTP
28101932810531339ribosomal subunit interface proteinQuickGO ontologyBLASTP
281078228119421161P-proteinQuickGO ontologyBLASTP
28119032812811909SMP-30GluconolaconaseLRE domain proteinQuickGO ontologyBLASTP