Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:2722492 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
27224922723223732pyridoxine 5-phosphate synthaseQuickGO ontologyBLASTP
27232352723963729DNA repair protein RecOQuickGO ontologyBLASTP
27239752724880906GTP-binding protein EraQuickGO ontologyBLASTP
27248772725614738ribonuclease IIIQuickGO ontologyBLASTP
27258312726805975signal peptidase IQuickGO ontologyBLASTP
272682227286211800GTP-binding protein LepAQuickGO ontologyBLASTP
272905027305191470leucine-rich repeat proteinQuickGO ontologyBLASTP
27307232730854132hypothetical proteinBLASTP
27318542731973120integrase catalytic regionQuickGO ontologyBLASTP
27333692733947579phage tail assembly proteinQuickGO ontologyBLASTP
27339372734761825appr-1-p processing enzyme family proteinQuickGO ontologyBLASTP
273475827371302373side tail fiber proteinQuickGO ontologyBLASTP
27371842737426243hypothetical proteinBLASTP
273746527408273363host specificity proteinQuickGO ontologyBLASTP
27408892741395507bacteriophage lambda tail assembly protein IQuickGO ontologyBLASTP