Pre_GI Gene

Some Help

Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:25751 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
2510525791687chaperone protein FimCQuickGO ontologyBLASTP
25751284172667outer membrane usher protein FimDQuickGO ontologyBLASTP
28418294251008mannose binding protein FimHQuickGO ontologyBLASTP
2946529971507fimbrial subunitQuickGO ontologyBLASTP
2998730505519fimbrial subunitQuickGO ontologyBLASTP
3047131202732fimbrial chaperoneQuickGO ontologyBLASTP
3126732112846BcfHQuickGO ontologyBLASTP
3215132438288hypothetical proteinBLASTP
3253832987450hypothetical proteinBLASTP
33357343611005putative transcriptional regulatorQuickGO ontologyBLASTP
3495035069120hypothetical protein
35332370501719arylsulfotransferaseQuickGO ontologyBLASTP
370963865815635-Nucleotidase domain proteinQuickGO ontologyBLASTP
3876639527762putative outer membraneexported proteinQuickGO ontologyBLASTP
40122416151494sulfataseQuickGO ontologyBLASTP
41717429041188chondroitin sulfateheparin utilization regulation proteinQuickGO ontologyBLASTP
42929441761248putative cytoplasmic proteinQuickGO ontologyBLASTP
44303460181716arylsulfotransferaseQuickGO ontologyBLASTP
46181473471167NaH antiporter NhaAQuickGO ontologyBLASTP
4741548308894transcriptional activator protein NhaRQuickGO ontologyBLASTP