Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:2342672 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
234267223450382367leucine-rich repeat proteinQuickGO ontologyBLASTP
23453552345474120hypothetical proteinBLASTP
23457062346548843side tail fiber proteinQuickGO ontologyBLASTP
23467682346989222putative homolog of virulence protein MsgAQuickGO ontologyBLASTP
23471812347738558putative outer membrane proteinQuickGO ontologyBLASTP
23484742349121648nitratenitrite response regulator protein NarPQuickGO ontologyBLASTP
234916523502081044cytochrome c-type biogenesis protein H2QuickGO ontologyBLASTP
23502052350762558thioldisulfide interChange protein DsbEQuickGO ontologyBLASTP
235075923526901932cytochrome c-type biogenesis protein CcmFQuickGO ontologyBLASTP
23526872353166480ABC superfamilyQuickGO ontologyBLASTP
23531632353375213hypothetical proteinBLASTP
23533722354118747ABC superfamilyQuickGO ontologyBLASTP
23541612354820660heme exporter protein CcmBQuickGO ontologyBLASTP
23548172355440624heme ABC exporter ATP-binding protein CcmAQuickGO ontologyBLASTP
23554552356057603cytochrome c-type protein napCQuickGO ontologyBLASTP
23560672356516450periplasmic nitrate reductase diheme cytochrome c subunitQuickGO ontologyBLASTP
23566322357501870ferredoxin-type protein NapHQuickGO ontologyBLASTP
23574882358183696periplasmic nitrate reductase NapGQuickGO ontologyBLASTP
235819023606762487periplasmic nitrate reductase large subunitQuickGO ontologyBLASTP
23609262361417492ferredoxin-type protein NapFQuickGO ontologyBLASTP
23618192362325507ecotinQuickGO ontologyBLASTP
236252523641681644ABC transporter ATP-binding protein YojIQuickGO ontologyBLASTP
23642442364894651alpha-ketoglutarate-dependent dioxygenase AlkBQuickGO ontologyBLASTP
236489723659551059regulatory protein adaQuickGO ontologyBLASTP
236603923670911053thiamine biosynthesis lipoprotein ApbEQuickGO ontologyBLASTP