Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:1750000 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
17500181750533516methylated-dna--protein-cysteine methyltransferaseQuickGO ontologyBLASTP
17507291751481753fumarate and nitrate reduction regulatory proteinQuickGO ontologyBLASTP
17516321752579948universal stress protein EQuickGO ontologyBLASTP
17526341752888255putative inner membrane proteinQuickGO ontologyBLASTP
175312717541581032MscS family inner membrane protein YnaIQuickGO ontologyBLASTP
17542441754846603transcriptional regulator CroCI familyQuickGO ontologyBLASTP
17548901755576687B34 domain proteinQuickGO ontologyBLASTP
17556041755942339hypothetical proteinBLASTP
17560481756566519putative thiol peroxidaseQuickGO ontologyBLASTP
17567011757525825hypothetical proteinBLASTP
175755217595341983hypothetical proteinBLASTP
17596091760205597hypothetical proteinBLASTP
17607541761605852putative regulatory proteinQuickGO ontologyBLASTP
176199717631061110putative cytoplasmic proteinQuickGO ontologyBLASTP
17633201763481162putative outer membrane lipoproteinQuickGO ontologyBLASTP
17636851764275591transcriptional regulator TetR familyQuickGO ontologyBLASTP
17643531765066714short-chain dehydrogenasereductase SDRQuickGO ontologyBLASTP
1765157176602687025-diketo-D-gluconic acid reductase AQuickGO ontologyBLASTP
17662171766342126hypothetical proteinBLASTP
17663031767208906regulatory protein LysRLysR substrate-bindingQuickGO ontologyBLASTP
17673271768256930isoflavone reductaseQuickGO ontologyBLASTP
176835317699661614periplasmic murein peptide-binding proteinQuickGO ontologyBLASTP
17701561770884729peptidase M14C familyQuickGO ontologyBLASTP
17708591771824966mandelate racemase muconate lactonizing enzyme N- domain proteinQuickGO ontologyBLASTP
17719401772446507thiol peroxidaseQuickGO ontologyBLASTP