Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:1709612 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
170961217109551344putative cytoplasmic proteinQuickGO ontologyBLASTP
17112481712171924LysR substrate binding domain proteinQuickGO ontologyBLASTP
171223217138571626methyl-accepting chemotaxis protein IIIQuickGO ontologyBLASTP
171402617151441119S-hydroxymethylglutathione dehydrogenaseclass III alcohol dehydrogenaseQuickGO ontologyBLASTP
17151761715451276putative cytoplasmic proteinQuickGO ontologyBLASTP
17162141716339126hypothetical proteinBLASTP
17163591716514156hypothetical proteinBLASTP
17165041717220717putative inner membrane proteinQuickGO ontologyBLASTP
17174041717517114hypothetical proteinBLASTP
171764617188721227secreted effector proteinQuickGO ontologyBLASTP
17189931719337345cyanate transportQuickGO ontologyBLASTP
17202441721005762putative periplasmic binding proteinQuickGO ontologyBLASTP
17210121721659648putative ABC transporter permease componentQuickGO ontologyBLASTP
17216841722415732ABC transporter ATP-binding subunitQuickGO ontologyBLASTP
17224121723092681putative ABC-type transport system membrane componentQuickGO ontologyBLASTP
172322917247791551putative inner membrane proteinQuickGO ontologyBLASTP
17251951725905711methyltransferase type 12QuickGO ontologyBLASTP
17261761726706531cytochrome B561QuickGO ontologyBLASTP
17268231727623801protein YdcFQuickGO ontologyBLASTP
172768717315893903ATP-dependent helicase HrpAQuickGO ontologyBLASTP
17317901732395606fmn-dependent NADH-azoreductaseQuickGO ontologyBLASTP
17323921732841450glutathione-dependent formaldehyde-activating GFAQuickGO ontologyBLASTP
17329841733307324YdbLQuickGO ontologyBLASTP
17333151733506192hypothetical proteinBLASTP
173350617361422637hypothetical proteinBLASTP